Monday 5 July 2021

Time to unravel Covid Origins mystery Part-1

Someone rightly pointed that the timeline henceforth depicting BC and AC would now be recalled as Before Corona and After Corona. Rightly so, given the scale of devastation, death, despair, gloom and misery Corona virus pandemic, World will be never the same again. More than 18 months to the pandemic, in this era of fourth generation of industrial revolution, people are still awaiting answers to the origins of the Corona Virus that literally shook the ground beneath their feet. The pandemic has thus far, claimed more than 3.5 million lives, displaced millions of people, caused loss of livelihoods and shattered developing economies.

For all the colossal devastation heaped the humanity deserves to know the origins of pandemic. Instead of a collective, sober and unbiased analysis, misplaced political interests and priorities have scuttled all the effort to investigate the origins.

The timeline of events since the public declaration of the viral outbreak has been replete of missteps, abdication, complicity and a reclusive approach. First, the World Health Organisation, the international body which leads the global responses to health calamity shocked the World with its complacency. As the casualty figures began to mount and the scale of infection spread manifold, the scientific community tasked with job of investigating the outbreak with an open-mind delivered a judgement on the virus on Feb 18th, 2020 ahead of WHO’s declaration of COVID-19 as pandemic on March 11th 2020.

Scientists support natural Origins of Covid-19

Foreclosing any debate to alternative theories pertaining to Covid-19, a group of 27 scientists in their letter to the Lancet, titled, “Statement in support of the scientists, public health professionals, and medical professionals of China combatting COVID-19” stated, “the rapid, open and transparent sharing of data on this outbreak is now being threatened by rumours and misinformation around its origins. We stand together to strongly condemn all the conspiracy theories suggesting that COVID-19 doesn’t have a natural origin1.  Ironically, by dismissing all the alternate voices as rumours and misinformation in one fell swoop, the group of public health scientists have blockaded any debate on the origins of the pandemic.

Soon this group which suggested a natural origin for Covid-19 hinged on a March 17th paper in Nature Medicine, “The Proximal Origins of SARS-CoV-2” by Kristian Andersen2. From here matters get really interesting as we look a close at the people behind this endorsement and research. Kristian Andersen’s paper has been in dock for being self-contradictory as it first says that “SARS-CoV-2 is not laboratory construct”, but in the discussion, it subtly changes the track stating that this is not manipulated from related SARS-CoV virus.

Indeed, ensnared by his flip-flops Andersen deleted his own tweets. In an interview Dr Fauci, the head of National Institute of Allergy and Infectious Diseases (NIAID) of NIH (National Institute of Health) disclosed that at a teleconference of the scientists on Feb 1st, just two days after WHO has raised the alert of Corona virus, Andersen first by phone and later by e-mail indicated that the genetic structure of the virus suggested that it was engineered. This view was backed by Australian scientist Edward Holmes, who reportedly said, “all find the genome inconsistent with expectations from evolutionary biology”3.

The teleconference was attended by NIH Director Francis Collins, Wellcome Trust Director Jeremy Farrar. In fact, a huge tranche of emails of Fauci made public under Freedom for Information Act by NIH shed more light on the details.  Fauci indicated that Farrar was in touch with WHO’s Tedros and was supposed to “give head’s up”. Three days after the conference, Andersen expressed doubts over the engineering of virus and termed all the suggestions pointing to it as “fringe” and “crackpot theories”. Hence forth, scientists strongly argued in favour of natural origins based on the Andersen and Holmes paper and dismissed all alternate voices as “conspiracy theories”.

Given the glaring inconsistencies, staring in face, it is important now to look at the Letter by experts group in the Lancet closely which has set the “narrative”. Setting narratives is common in politics. Science is known to be fair, rigorous and open encouraging debate and diverse thoughts. But the unwillingness of the scientists to admit any alternative perspective on the origins of the virus has set alarm bells ringing.

Grant Details and Scientists involved in Corona Virus Research

Interestingly, the Lancet’s solidarity letter and the Nature publication are spear-headed by scientists who had vested interests in the Corona virus research. The NIH through the NIAID headed by Fauci, awarded $ 3.4 million grant to the project titled – “Understanding the Risk of Bat Corona Emergence” in 2014 and 2015. The grants were assigned to Peter Daszak4, the head of the EcoHealth Alliance (EHA) of New York who subcontracted the them to Shi Zhengh Li, the expert Virologist at Wuhan Institute of Virology (WIV) famous now as “Bat woman”.

Shi teamed with Ralph Baric of University of North Carolina, an ace expert on gain-of-function (GOF) research and created a novel virus with the backbone of SARS-CoV1 and replaced its spike protein with that of a bat in 2015. Around the same time, a moratorium was imposed on GOF research in America following the incidents of lab accidents involving anthrax and H5 N1 bird flu virus.  Subsequently authorities called for a “pause” on GOF research on virus related to Influenza, MERS, SARS.

The moratorium had a clause which permitted the continuation of “such experiments which are urgent and necessary to protect public health or national security5. Since the funds continued to flow uninterruptedly to Shi, the director of NIAID and NIH Francis Collins may have invoked the exemption.

GOF refers to increasing the transmissibility, virulence and immunogenicity of microorganisms through serial passaging. Baric taught Shi a method for engineering bat corona viruses to attack other species. They used human cells grown in culture (for invitro tests) and humanised mice (in vivo experiments) to assess the infectivity. Soon she began constructing the chimeric viruses.

Interestingly, Daszak just before the public disclosure of the corona outbreak informed about the 100 Chimeric SARS viruses engineered in WIV. In an interview on December 19th, 2019, he even conceded that Corona viruses can be easily manipulated in the lab6. He concluded by saying that the spike protein sequences of the chimeric viruses can be used to make vaccines against the viral outbreak.

Daszak had first-hand account of the Corona virus research at WIV. Instead of aiding in mitigation efforts, he chose to defend the research and outrightly expressed solidarity to Chinese scientists even as countries were grappling with virus outbreak.

For over 20 years EHA has been funding the research on Virus which makes them potentially dangerous than what they exist in nature. On the premise that they can get ahead of the nature and be well prepared to handle any natural spill overs through zoonotic transmission, they defended engineering of virus. Hence, any theory substantially firming up the argument of lab leak would be a devastating blow to EHA.

Connecting the Dots

Instead of declaring conflicting interests before advocating the natural origins of Covid-19, Daszak worked behind the scenes. He marshalled expert scientists to condemn all theories suggesting Covid-19 doesn’t have a natural origin as conspiracy theory.

Signatories of The Lancet letter included Daszak and 26 public health experts. Of them, two scientists are from EHA, two associated with Daszak as part of leadership of the Global Virome Project, four collaborators of Ralph Baric, an editor of ProMED which receives operational support from Wellcome group7. In all, baring three people who are not in active research most of them as of now have reversed or modified their position.

For the fear of staking their own reputation the bigwigs of science community created a perception that questioning or doubting their natural origins theory of Covid-19 a taboo. Months into Covid outbreak due to politically charged atmosphere in Trump regime, any discussion on the lab-leak theory was construed as racist.

By April 2020, Trump called out China for the “Wuhan Outbreak” and even halted funds to WHO “for failing in its duty”. Coming under intense criticism over pandemic management, Trump cancelled funds to EHA for funding the Corona virus research at WIV. In response to Trump’s decision, the scientists intensely rallied the lab-leak as conspiracy, brought immense pressure on the Trump administration to revoke the decision. 77 Nobel Laureates, 33 scientific societies penned an open letter to Trump to reconsider the decision8.

For the fear of being associated the Trump, who first advocated a Wuhan lab leak, scientists refrained from discussing the lab leak theory. Labelling lab-leak as conspiracy theory, media actively churned several videos in support of natural origins. As elections neared discussions any contradictory opinions to natural origins of Covid were deemed blasphemous.

As of now, three hypotheses are in vogue- first, virus has evolved naturally and entered humans through animals; second, virus evolved naturally, but employee in the lab who might have contracted the virus has spilled it to society; third, scientists at lab are manipulating the virus and that it accidentally or intentionally spilled out.

Shortly, after NIH’s revocation of funds to EHA, Daszak in an interview to Nature lamented that NIH’s funding couldn’t be reinstated until seven demands are met. He recounting that EHA was asked to obtain a sample vial of SARS-CoV-2 from WIV for genome analysis and to arrange an inspection of WIV for federal officials. Terming NIH’s conditions as heinous and that his research was caught in cross-hairs. He stubbornly ruled out any other possibility and construed any dissenting voice as conspiracy theory9. Shi Zhengli voiced similar concerns and called NIH’s conditions as outrageous. Since 2013, EHA is reported to have received $39 million and as of now the amount that ended up in Wuhan is not clear. Additionally, EHA received $123 million between 2017 and 2020 from the government with Department of Defense (DoD) being one of the biggest funders10.

Being an election year, Covid has become a political agenda. Unfortunately, scientific temper was abjectly surrendered at the political altar. While domestic politics of America inflicted a fatal blow to the unflinching scientific efforts to gain greater clarity, an objective dissection of scientific pursuits to unravel the truth laid out bare the menacing perfidy of scientists and academic journals.

Indeed, the left-leaning mainstream media, lent credence to theory of natural origins of Corona virus. Social media censored and ruthlessly pulled down any references to lab-leak. Newspapers too followed similar suit for over one year. The political polarisation cast a huge shadow on the scientific discussions. The “deep state” which drives the narratives actually made it difficult even for the secretary of the State Mike Pompeo to get the real intelligence reports on the Covid origins. However, the tide turned to change the moment President Biden hinted at an alternate hypothesis and ordered an investigation.

Systematic gaslighting of Covid origins

As the pandemic continued to rage, some scientists daringly admitted that the remarkable infectivity rate of the virus points to some manipulation. They haven’t ruled out lab-leak. One of the earliest papers by the Indian scientists who claimed a similarity between the sequences of SARS-2 spike protein to HIV-1 gp120 and gag protein was forced to retract11. Similarly, scientists who alluded to genetic manipulation of the virus were either rejected or their reviews were inadvertently delayed.

Social media was abounded with several such stories and harrowing experiences of the scientists who had to wait for an inordinately long time to get a response. On the contrary papers which promoted the Chinese perspective were published in a span of just 9 nine days12. Interestingly, this trend reversed after the political dispensation began to embrace and give a chance to the “lab-leak” hypothesis.

At the centre of this entire scandalous approach have been the science journals. By scuttling the debate, shutting the alternate voices and stalling an open discussion the elixir of science, the journals have invariably demonstrated their comprised credentials. In lieu of their inextricable political leanings, outright rejection of the lab-leak hypothesis by science journals raised concerns about the erosion of genuine scientific temper. Clearly, science should have been delineated from politics to have an unbiased, rational and objective investigation.

The Lancet, considered a gold standard of medical journalism, gearing up to celebrate its 200th anniversary emerged as the centre of the Covid origins scandal. By denying platform to dissenting voices, it has formidably upheld the views that are favourable to China. Mirroring its shifting priorities and political allegiances, The Lancet expressed serious concerns over the use of Hydroxychloroquine (HCQ) manufactured in India for Covid treatment forcing the WHO to suspend its usage. Now latest studies suggest that HCQ reduced Covid mortality.

Large-scale clinical trials in Singapore reported of the effectiveness of HCQ in reducing Covid spread13. India has been at the receiving end of The Lancet’s implicit bias, which became evident when its editorial lashed out at New Delhi for abrogation of Article 370 and castigated the Modi government of Covid handling. Clearly, both the issues, the internal affairs of India are beyond the realm of a medical journal. But have an undeclared China connect to them.

The Lancet’s connections with China are so inextricable that it picked up Peter Daszak, director of EHA to be part of the Lancet COVID-19 Commission 12-member taskforce constituted to investigate the origins of the SARS-CoV-2. Along the expected lines, the team assessed a zoonotic spill over from an intermediate host as “likely to very likely” and a laboratory incident as “extremely unlikely14

It is interesting to note that The Lancet is part of the Rockefeller foundation funded “Planetary Health Alliance” which includes EHA, Wellcome Trust, Harvard T. H Chan School of Public Health, Project Drawdown and Stockholm Institute15. In short, the journal is hand-in-glove with the agency that has funded the Corona research and by consequence shields China from any criticism.

In January, the editor of The Lancet rejected letter of The Paris group, a group of 14 experts that called for an open investigation on the origins of the Covid-19. In May 2020, in defence of China, Horton in an interview to CCTV said, “it wasn’t scientific” and “not helpful” to seek the details of the patient zero and such efforts could be “highly stigmatizing” and “discriminatory”. It is very important to understand the origin of this virus and to study those origins scientifically and not allow such conspiracy theories to contaminate our thinking” but these would only “end risk destabilising our response to the virus16.

In Guardian Horton wrote, “but to blame China of the pandemic is to rewrite history of Covid-19 and to marginalise the failings of the Western nations17. The job of science is to chase the truth and make inferences based on the data and verifiable evidence. Horton’s stance and eventual free pass prompted Daszak to sneer at MI6 Head Sir Richard Dearlove for suggesting that covid escaped from the lab.

Journals Nature and Science also refused to carry critical articles of dissenting scientists. Nature indeed, published paper submitted by Shi and two others on the same day of submission. This paper didn’t cite the virus RaTG13 that caused the death of three miners in the Yunnan caves to the SARS-CoV-2. The absence of the critical missing link created a confusion. Despite several requests, Nature published the addendum only after 10 months in November. Nature also published a series of papers which created a false trail of the Pangolin present in the Wuhan wet market as intermediary in infection. But when a scientist pointed that all the four papers used samples from same batch of pangolins, Nature rejected the submission.


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